Keep it clean. Keep it simple. To wash your prescription eyeglass lenses, eye care professionals suggest you gently rub your lenses clean with your fingers using warm, soapy water. Rinse them, and then pat them dry with a clean, soft cloth. Many optical suppliers sell ultra-fine, machine-washable microfiber lens cleaning cloths that trap dirt and dust. Try to avoid rubbing prescription lenses with rags, facial tissues or paper towels, as they could scratch your lenses. And definitely avoid using household cleaners, acetone or soaps with cream—as chemicals may damage your frames.